| South Branch Meduxnekeag River | |
|---|---|
| Origin | Maine |
| Mouth | Meduxnekeag River |
| Progression | Meduxnekeag — St. John — Bay of Fundy |
| Basin countries | United States, Canada |
| Length | about 25 miles (40 km) |
| Mouth elevation | 300 feet (90 m) |
The North Branch Meduxnekeag River is a river in Aroostook County, Maine and Carleton County, New Brunswick. From the outlet of a small pond () in Maine Township 8, Range 3, WELS, the river runs about 20 miles (30 km) northeast, south, and east to the Canada – United States border, crossing into Canada at . It runs about 4 miles (6 km) southeast to its confluence with the Meduxnekeag River in Wakefield, NB.